Vanni has been awarded a grant from the NIAID to apply new mathematical to improve treatment of intestinal disease. The work will be to predict the effects of broad spectrum antibiotics affect the dynamics of the microbiome. The goal is to identify microbiome patterns and develop strategies to speed recovery or prevent disease in the first place.
Read the UMass Dartmouth press release here:
UMass Dartmouth Professor earns…
Vanni was a co-author of a recent Nature article–“Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile“– where that the gut commensal bacterium Clostridium scindens is associated with resistance to C. difficile. C. scindens metabolizes bile salts to produce inhibitors of C. difficile. Very exciting!